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                              July 17, 2023

       Daniel Jones
       Chief Executive Officer
       SeqLL, Inc.
       3 Federal Street
       Billerica, MA 01821

                                                        Re: SeqLL, Inc.
                                                            Registration
Statement on Form S-1
                                                            Filed June 23, 2023
                                                            File No. 333-272908

       Dear Daniel Jones:

              We have reviewed your registration statement and have the
following comments. In
       some of our comments, we may ask you to provide us with information so
we may better
       understand your disclosure.

              Please respond to this letter by amending your registration
statement and providing the
       requested information. If you do not believe our comments apply to your
facts and
       circumstances or do not believe an amendment is appropriate, please tell
us why in your
       response.

              After reviewing any amendment to your registration statement and
the information you
       provide in response to these comments, we may have additional comments.

       Registration Statement on Form S-1 Filed June 23, 2023

       The Offering, page 6

   1.                                                   We note your disclosure
on page 7 that you refer to an "initial offering price." We believe
                                                        this to be a typo, but
please clarify.
   2.                                                   We note your disclosure
that there is no established public market for the Warrants being
                                                        registered. Please
describe the factors considered in determining the exercise price of the
                                                        warrants. Refer to Item
505(b) of Regulation S-K.
 Daniel Jones
FirstName
SeqLL, Inc.LastNameDaniel Jones
Comapany
July       NameSeqLL, Inc.
     17, 2023
July 17,
Page  2 2023 Page 2
FirstName LastName
Risk Factors, page 11

3.       We note that in your preliminary proxy statement, filed June 5, 2023,
you included a risk
         factor detailing the risks associated with substantial transaction
costs in connection with
         the Merger. Please include this risk factor in this registration
statement or explain why it is
         not material.
4.       We note that in your preliminary proxy statement, filed June 5, 2023,
you included a risk
         factor detailing the risks associated with actions taken by SeqLL's
officers and directors to
         increase the likelihood of approval of the Merger having a depressive
effect on the price
         of your common stock. Please include this risk factor in this
registration statement or
         explain why it is not material.
5.       We note recent instances of extreme stock price run-ups followed by
rapid price declines
         and stock price volatility seemingly unrelated to company performance
following a
         number of recent public offerings, particularly among companies with
relatively smaller
         public floats. Revise to include a separate risk factor, or supplement
an existing risk
         factor, addressing the potential for rapid and substantial price
volatility and discuss the
         risks to investors when investing in stock where the price is changing
rapidly. Clearly
         state that such volatility, including any stock-run up, may be
unrelated to your actual or
         expected operating performance and financial condition or prospects,
making it difficult
         for prospective investors to assess the rapidly changing value of your
stock.
Risks Related to this Offering and Ownership of Our Common Stock and Warrants
We do not anticipate paying any cash dividends on our common stock in the
foreseeable future
and, as such, capital appreciation, if any..., page 29

6.       We note your disclosure on page 3 that you will be declaring a cash
dividend as a
         requirement of the Merger Agreement. However, your risk factor here
states that you
         "have never declared or paid cash dividends." Please clarify this
discrepancy. Make
         consistent changes under "Dividend Policy," on page 33.
General

7.       Please see our comments on the Proxy Statement filed June 5, 2023 and
apply them here,
         as applicable.
        We remind you that the company and its management are responsible for
the accuracy
and adequacy of their disclosures, notwithstanding any review, comments, action
or absence of
action by the staff.

       Refer to Rules 460 and 461 regarding requests for acceleration. Please
allow adequate
time for us to review any amendment prior to the requested effective date of
the registration
statement.
 Daniel Jones
SeqLL, Inc.
July 17, 2023
Page 3

        You may contact Ta Tanisha Meadows at 202-551-3322 or Theresa Brillant
at 202-551-
3307 if you have questions regarding comments on the financial statements and
related
matters. Please contact Nicholas Nalbantian at 202-551-7470 or Mara Ransom at
202-551-3264
with any other questions.



                                                        Sincerely,
FirstName LastNameDaniel Jones
                                                        Division of Corporation
Finance
Comapany NameSeqLL, Inc.
                                                        Office of Trade &
Services
July 17, 2023 Page 3
cc:       Eric M. Hellige
FirstName LastName