United States securities and exchange commission logo





                              December 19, 2023

       Daniel Jones
       Chief Executive Officer
       SeqLL, Inc.
       3 Federal Street
       Billerica, MA 01821

                                                        Re: SeqLL, Inc.
                                                            Registration
Statement on Form S-1
                                                            Response Letter
Dated December 18, 2023
                                                            File No. 333-272908

       Dear Daniel Jones:

            We have reviewed your response dated December 18, 2023 and have the
following
       comments.

              Please respond to this letter by amending your registration
statement and providing the
       requested information. If you do not believe a comment applies to your
facts and circumstances
       or do not believe an amendment is appropriate, please tell us why in
your response.

              After reviewing any amendment to your registration statement and
the information you
       provide in response to this letter, we may have additional comments.
Unless we note otherwise,
       any references to prior comments are to comments in our December 15,
2023 letter.

       Response Dated December 18, 2023

       Cover Page

   1.                                                   We note your response
to comment 1. Please file a pre-effective amendment in which you
                                                        clearly disclose which
over-the-counter market your shares are quoted on. Refer to Item
                                                        501(b)(4) of Regulation
S-K.
       Lyneer Investments, LLC and Subsidiaries Financial Statements
       Condensed Consolidated Balance Sheets, page F-2

   2.                                                   We read your response
to comment 3 and note you expect to receive a waiver from the
                                                        lender of all existing
events of default under the debt instruments, but the agreements have
                                                        not yet been executed.
Please file the signed and dated agreements as exhibits in a pre-
                                                        effective amendment.
Refer to Item 601(b)(10) of Regulation S-K. We may have
                                                        additional comments
after our review of the agreements.
 Daniel Jones
SeqLL, Inc.
December 19, 2023
Page 2
Note 3. Summary of Significant Accounting Policies
Liquidity, page F-7

3.    We read your response to comment 4 and note you did not address the
short-term nature
      of the extension. Please revise to disclose your plans to meet debt
obligations and cure all
      violations after February 26, 2024.
        Please contact Tatanisha Meadows at 202-551-3322 or Theresa Brillant at
202-551-3307
if you have questions regarding comments on the financial statements and
related matters. Please
contact Rucha Pandit at 202-551-6022 or Erin Jaskot at 202-551-3442 with any
other questions.



                                                            Sincerely,
FirstName LastNameDaniel Jones
                                                            Division of
Corporation Finance
Comapany NameSeqLL, Inc.
                                                            Office of Trade &
Services
December 19, 2023 Page 2
cc:       Eric M. Hellige
FirstName LastName